FTLD targets brain regions expressing recently evolved genes

In frontotemporal lobar degeneration (FTLD), pathological protein aggregation is associated with a decline in human-specialized social-emotional and language functions. Most disease protein aggregates contain either TDP-43 (FTLD-TDP) or tau (FTLD-tau). Here, we explored whether FTLD targets brain re...

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Detalles Bibliográficos
Autores principales: Pasquini, Lorenzo, Pereira, Felipe L., Seddighi, Sahba, Zeng, Yi, Wei, Yongbin, Illán-Gala, Ignacio, Vatsavayai, Sarat C., Friedberg, Adit, Lee, Alex J., Brown, Jesse A., Spina, Salvatore, Grinberg, Lea T., Sirkis, Daniel W., Bonham, Luke W., Yokoyama, Jennifer S., Boxer, Adam L., Kramer, Joel H., Rosen, Howard J., Humphrey, Jack, Gitler, Aaron D., Miller, Bruce L., Pollard, Katherine S., Ward, Michael E., Seeley, William W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635220/
https://www.ncbi.nlm.nih.gov/pubmed/37961381
http://dx.doi.org/10.1101/2023.10.27.23297687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635220/
https://www.ncbi.nlm.nih.gov/pubmed/37961381
http://dx.doi.org/10.1101/2023.10.27.23297687

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