A multidimensional analysis reveals distinct immune phenotypes and tertiary lymphoid structure-like aggregates in the bone marrow of pediatric acute myeloid leukemia

Because of the low mutational burden, children with acute myeloid leukemia (AML) are thought to have a ‘cold’ tumor microenvironment and consequently, a low likelihood of response to T cell-directed immunotherapies. Here, we provide a multidimensional overview of the tumor immune microenvironment in...

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Detalles Bibliográficos
Autores principales: Koedijk, Joost B., van der Werf, Inge, Penter, Livius, Vermeulen, Marijn A., Barneh, Farnaz, Perzolli, Alicia, Meesters-Ensing, Joyce I., Fiocco, Marta, de Groot-Kruseman, Hester A., Moeniralam, Rubina, Christensen, Kristina Bang, Porter, Billie, Pfaff, Kathleen, Garcia, Jacqueline S., Rodig, Scott J., Wu, Catherine J., Hasle, Henrik, Nierkens, Stefan, Belderbos, Mirjam E., Zwaan, C. Michel, Heidenreich, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635226/
https://www.ncbi.nlm.nih.gov/pubmed/37961528
http://dx.doi.org/10.1101/2023.03.03.23286485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635226/
https://www.ncbi.nlm.nih.gov/pubmed/37961528
http://dx.doi.org/10.1101/2023.03.03.23286485

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