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K-Nearest-Neighbors Induced Topological PCA for Single Cell RNA-Sequence Data Analysis

Single-cell RNA sequencing (scRNA-seq) is widely used to reveal heterogeneity in cells, which has given us insights into cell-cell communication, cell differentiation, and differential gene expression. However, analyzing scRNA-seq data is a challenge due to sparsity and the large number of genes inv...

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Detalles Bibliográficos
Autores principales: Cottrell, Sean, Hozumi, Yuta, Wei, Guo-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cornell University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635285/
https://www.ncbi.nlm.nih.gov/pubmed/37961744