Cargando…

Engineering Tripartite Gene Editing Machinery for Highly Efficient Non-Viral Targeted Genome Integration

Non-viral DNA donor template has been widely used for targeted genomic integration by homologous recombination (HR). This process has become more efficient with RNA guided endonuclease editor system such as CRISPR/Cas9. Circular single stranded DNA (cssDNA) has been harnessed previously as a genome...

Descripción completa

Detalles Bibliográficos
Autores principales: Nam, Hangu, Xie, Keqiang, Majumdar, Ishita, Yang, Shaobo, Starzyk, Jakob, Lee, Danna, Shan, Richard, Li, Jiahe, Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635301/
https://www.ncbi.nlm.nih.gov/pubmed/37961210
http://dx.doi.org/10.21203/rs.3.rs-3365585/v1