Expansion of endogenous T cells in CSF of pediatric CNS tumor patients undergoing locoregional delivery of IL13R〿2-targeting CAR T cells: an interim analysis

Outcomes for pediatric brain tumor patients remain poor, and there is optimism that chimeric antigen receptor (CAR) T cell therapy can improve prognosis. Here, we present interim results from the first six pediatric patients treated on an ongoing phase I clinical trial (NCT04510051) of IL13BBζ-CAR T...

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Detalles Bibliográficos
Autores principales: Wang, Leo, Oill, Angela Taravella, Blanchard, M., Wu, Melody, Hibbard, Jonathan, Sepulveda, Sean, Peter, Lance, Kilpatrick, Julie, Munoz, Margarita, Stiller, Tracey, Shulkin, Noah, Wagner, Jamie, Dolatabadi, Ally, Nisis, Monica, Shepphird, Jennifer, Sanchez, Gabriela, Lingaraju, Chetan, Manchanda, Mishika, Natri, Heini, Kouakanou, Léonce, Sun, Grace, Oliver-Cervantes, Cheryl, Georges, Joseph, Aftabizadeh, Maryam, Forman, Stephen, Priceman, Saul, Ressler, Julie, Arvanitis, Leonidas, Cotter, Jennifer, D’Apuzzo, Massimo, Tamrazi, Benita, Badie, Behnam, Davidson, Tom, Banovich, Nicholas, Brown, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635314/
https://www.ncbi.nlm.nih.gov/pubmed/37961215
http://dx.doi.org/10.21203/rs.3.rs-3454977/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635314/
https://www.ncbi.nlm.nih.gov/pubmed/37961215
http://dx.doi.org/10.21203/rs.3.rs-3454977/v1

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