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Placental RNA sequencing implicates IGFBP1 in insulin sensitivity during pregnancy and in gestational diabetes

Reduced insulin sensitivity (or greater insulin resistance) is a hallmark of normal physiology in late pregnancy and also underlies gestational diabetes mellitus (GDM) pathophysiology. We conducted transcriptomic profiling of 434 human placentas and identified a strong positive association between i...

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Detalles Bibliográficos
Autores principales: Hivert, Marie-France, White, Frederique, Allard, Catherine, James, Kaitlyn, Majid, Sana, Aguet, François, Ardlie, Kristin, Edlow, Andrea, Florez, Jose, Bouchard, Luigi, Jacques, Pierre-Etienne, Karumanchi, S., Powe, Camille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635326/
https://www.ncbi.nlm.nih.gov/pubmed/37961187
http://dx.doi.org/10.21203/rs.3.rs-3464151/v1