Cargando…
Placental RNA sequencing implicates IGFBP1 in insulin sensitivity during pregnancy and in gestational diabetes
Reduced insulin sensitivity (or greater insulin resistance) is a hallmark of normal physiology in late pregnancy and also underlies gestational diabetes mellitus (GDM) pathophysiology. We conducted transcriptomic profiling of 434 human placentas and identified a strong positive association between i...
Autores principales: | Hivert, Marie-France, White, Frederique, Allard, Catherine, James, Kaitlyn, Majid, Sana, Aguet, François, Ardlie, Kristin, Edlow, Andrea, Florez, Jose, Bouchard, Luigi, Jacques, Pierre-Etienne, Karumanchi, S., Powe, Camille |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635326/ https://www.ncbi.nlm.nih.gov/pubmed/37961187 http://dx.doi.org/10.21203/rs.3.rs-3464151/v1 |
Ejemplares similares
-
SAT-123 Burden of Type 2 Diabetes Genetic Risk Alleles Differs Among Physiologic Subtypes of Gestational Diabetes Mellitus
por: Powe, Camille, et al.
Publicado: (2019) -
Interplay of Placental DNA Methylation and Maternal Insulin Sensitivity in Pregnancy
por: Hivert, Marie-France, et al.
Publicado: (2020) -
Defining Heterogeneity Among Women With Gestational Diabetes Mellitus
por: Powe, Camille E., et al.
Publicado: (2020) -
Genetic Determinants of Glycemic Traits and the Risk of Gestational Diabetes Mellitus
por: Powe, Camille E., et al.
Publicado: (2018) -
Genetic Loci and Physiologic Pathways Involved in Gestational Diabetes Mellitus Implicated Through Clustering
por: Powe, Camille E., et al.
Publicado: (2021)