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Microtubule-Mediated Regulation of β(2)AR Translation and Function in Failing Hearts

BACKGROUND: β(1)AR (beta-1 adrenergic receptor) and β(2)AR (beta-2 adrenergic receptor)-mediated cyclic adenosine monophosphate signaling has distinct effects on cardiac function and heart failure progression. However, the mechanism regulating spatial localization and functional compartmentation of...

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Detalles Bibliográficos
Autores principales: Kwan, Zoe, Paulose Nadappuram, Binoy, Leung, Manton M., Mohagaonkar, Sanika, Li, Ao, Amaradasa, Kumuthu S., Chen, Ji, Rothery, Stephen, Kibreab, Iyobel, Fu, Jiarong, Sanchez-Alonso, Jose L., Mansfield, Catherine A., Subramanian, Hariharan, Kondrashov, Alexander, Wright, Peter T., Swiatlowska, Pamela, Nikolaev, Viacheslav O., Wojciak-Stothard, Beata, Ivanov, Aleksandar P., Edel, Joshua B., Gorelik, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635332/
https://www.ncbi.nlm.nih.gov/pubmed/37869877
http://dx.doi.org/10.1161/CIRCRESAHA.123.323174