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Busulfan Interlaboratory Proficiency Testing Program Revealed Worldwide Errors in Drug Quantitation and Dose Recommendations

BACKGROUND: The clinical outcomes of busulfan-based conditioning regimens for hematopoietic cell transplantation (HCT) have been improved by personalizing the doses to target narrow busulfan plasma exposure. An interlaboratory proficiency test program for the quantitation, pharmacokinetic modeling,...

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Detalles Bibliográficos
Autores principales: Kweekel, Dina M., McCune, Jeannine S., Punt, Arjen M., van Luin, Matthijs, Franssen, Eric J.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Therapeutic Drug Monitoring 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635345/
https://www.ncbi.nlm.nih.gov/pubmed/37199431
http://dx.doi.org/10.1097/FTD.0000000000001107