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Cryo-EM and AFM visualize linear polyorganophosphazene: individual chains and single-chain assemblies with proteins

Polyorganophosphazenes are biodegradable macromolecules with potent immunoadjuvant activity that self-assemble with protein antigens to provide biological activity. Direct imaging by cryogenic electron microscopy reveals the coil structure of the highly-charged high molecular mass synthetic polyorga...

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Detalles Bibliográficos
Autores principales: Andrianov, Alexander, Hlushko, Raman, Pozharski, Edvin, Prabhu, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635375/
https://www.ncbi.nlm.nih.gov/pubmed/37961436
http://dx.doi.org/10.21203/rs.3.rs-3411603/v1