Immunoglobin and T cell receptor repertoire changes induced by a prototype vaccine against Chagas disease in naïve rhesus macaques

A vaccine against Trypanosoma cruzi, the agent of Chagas disease, would be an excellent additional tool for disease control. A recombinant vaccine based on Tc24 and TSA1 parasite antigens was found to be safe and immunogenic in naïve macaques. Here we performed a transcriptomic analysis of PBMC resp...

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Detalles Bibliográficos
Autores principales: Dumonteil, Eric, Tu, Weihong, Desale, Hans, Goff, Kelly, Marx, Preston, Ortega-Lopez, Jaime, Herrera, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635379/
https://www.ncbi.nlm.nih.gov/pubmed/37961272
http://dx.doi.org/10.21203/rs.3.rs-3453582/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635379/
https://www.ncbi.nlm.nih.gov/pubmed/37961272
http://dx.doi.org/10.21203/rs.3.rs-3453582/v1

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