A Single nucleotide polymorphism in the ALDH2 gene modifies the risk of esophageal squamous cell carcinoma in BRCA2 p.K3326* carriers

Esophageal squamous cell carcinoma (ESCC) has a very high incidence rate in northeastern Iran. Our team previously reported the BReast CAncer gene 2 (BRCA2) p.K3326* mutation as a moderately penetrant ESCC susceptibility variant in northern Iran (odds ratio (OR) = 3.64, 95% confidence interval (CI)...

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Detalles Bibliográficos
Autores principales: Zamani, Neda, Szymiczek, Agata, Shakeri, Ramin, Poustchi, Hossein, Pourshams, Akram, Narod, Steven, Malekzadeh, Reza, Akbari, Mohammad R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635553/
https://www.ncbi.nlm.nih.gov/pubmed/37943872
http://dx.doi.org/10.1371/journal.pone.0292611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635553/
https://www.ncbi.nlm.nih.gov/pubmed/37943872
http://dx.doi.org/10.1371/journal.pone.0292611

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