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A pig model of chronic hepatitis E displaying persistent viremia and a downregulation of innate immune responses in the liver

BACKGROUND: Hepatitis E virus (HEV) is a zoonotic virus transmitted by pig meat and responsible for chronic hepatitis E in immunocompromised patients. It has proved challenging to reproduce this disease in its natural reservoir. We therefore aimed to develop a pig model of chronic hepatitis E to imp...

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Detalles Bibliográficos
Autores principales: León-Janampa, Nancy, Caballero-Posadas, Ignacio, Barc, Céline, Darrouzain, François, Moreau, Alain, Guinoiseau, Thibault, Gatault, Philippe, Fleurot, Isabelle, Riou, Mickaël, Pinard, Anne, Pezant, Jérémy, Rossignol, Christelle, Gaudy-Graffin, Catherine, Brand, Denys, Marlet, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635601/
https://www.ncbi.nlm.nih.gov/pubmed/37938097
http://dx.doi.org/10.1097/HC9.0000000000000274