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Age-related decline in bone mineral transport and bone matrix proteins in osteoblasts from stromal stem cells

We studied osteoblast bone mineral transport and matrix proteins as a function of age. In isolated bone marrow cells from long bones of young (3 or 4 mo) and old (18 or 19 mo) mice, age correlated with reduced mRNA of mineral transport proteins: alkaline phosphatase (ALP), ankylosis (ANK), the Cl(−)...

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Detalles Bibliográficos
Autores principales: Tourkova, Irina L., Larrouture, Quitterie C., Onwuka, Kelechi M., Liu, Silvia, Luo, Jianhua, Schlesinger, Paul H., Blair, Harry C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635645/
https://www.ncbi.nlm.nih.gov/pubmed/37519232
http://dx.doi.org/10.1152/ajpcell.00227.2023