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Retrospective analysis of enhancer activity and transcriptome history

Cell state changes in development and disease are controlled by gene regulatory networks, the dynamics of which are difficult to track in real time. In this study, we used an inducible DCM–RNA polymerase subunit b fusion protein which labels active genes and enhancers with a bacterial methylation ma...

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Detalles Bibliográficos
Autores principales: Boers, Ruben, Boers, Joachim, Tan, Beatrice, van Leeuwen, Marieke E., Wassenaar, Evelyne, Sanchez, Erlantz Gonzalez, Sleddens, Esther, Tenhagen, Yasha, Mulugeta, Eskeatnaf, Laven, Joop, Creyghton, Menno, Baarends, Willy, van IJcken, Wilfred F. J., Gribnau, Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635829/
https://www.ncbi.nlm.nih.gov/pubmed/36823354
http://dx.doi.org/10.1038/s41587-023-01683-1