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Retrospective analysis of enhancer activity and transcriptome history
Cell state changes in development and disease are controlled by gene regulatory networks, the dynamics of which are difficult to track in real time. In this study, we used an inducible DCM–RNA polymerase subunit b fusion protein which labels active genes and enhancers with a bacterial methylation ma...
Autores principales: | Boers, Ruben, Boers, Joachim, Tan, Beatrice, van Leeuwen, Marieke E., Wassenaar, Evelyne, Sanchez, Erlantz Gonzalez, Sleddens, Esther, Tenhagen, Yasha, Mulugeta, Eskeatnaf, Laven, Joop, Creyghton, Menno, Baarends, Willy, van IJcken, Wilfred F. J., Gribnau, Joost |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635829/ https://www.ncbi.nlm.nih.gov/pubmed/36823354 http://dx.doi.org/10.1038/s41587-023-01683-1 |
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