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J147 ameliorates sepsis-induced depressive-like behaviors in mice by attenuating neuroinflammation through regulating the TLR4/NF-κB signaling pathway

Neuroinflammation is associated with the pathophysiology of depression. The molecular mechanism of depressive-like behavior caused by sepsis-associated encephalopathy (SAE) is incompletely understood. J147 (an analog of curcumin) has been reported to improve memory and has neuroprotective activity,...

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Detalles Bibliográficos
Autores principales: Qiu, Fang, Zeng, Changchun, Liu, Yuqiang, Pan, Haobo, Ke, Changneng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635911/
https://www.ncbi.nlm.nih.gov/pubmed/37676534
http://dx.doi.org/10.1007/s10735-023-10147-4