The interaction of bile acids and gut inflammation influences the pathogenesis of inflammatory bowel disease

Bile acids (BA) are amphipathic molecules originating from cholesterol in the liver and from microbiota-driven biotransformation in the colon. In the gut, BA play a key role in fat digestion and absorption and act as potent signaling molecules on the nuclear farnesoid X receptor (FXR) and membrane-a...

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Detalles Bibliográficos
Autores principales: Di Ciaula, Agostino, Bonfrate, Leonilde, Khalil, Mohamad, Portincasa, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635993/
https://www.ncbi.nlm.nih.gov/pubmed/37515676
http://dx.doi.org/10.1007/s11739-023-03343-3