Intra-articular delivery of geraniol encapsulated by pH/redox-responsive nanogel ameliorates osteoarthritis by regulating oxidative stress and inflammation

Osteoarthritis (OA) remains a challenging condition due to limited drug bioavailability within the avascular and dense cartilage matrix. This study introduces a pH/redox-responsive nanogel for enhanced delivery of geraniol in OA therapy. We investigated geraniol's role in preventing chondrocyte...

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Detalles Bibliográficos
Autores principales: Pan, Jun, Cai, Youzhi, Zhang, Chi, Xu, Sanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635995/
https://www.ncbi.nlm.nih.gov/pubmed/37848748
http://dx.doi.org/10.1007/s10735-023-10163-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635995/
https://www.ncbi.nlm.nih.gov/pubmed/37848748
http://dx.doi.org/10.1007/s10735-023-10163-4

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