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Immunogenic arenavirus vector SIV vaccine reduces setpoint viral load in SIV-challenged rhesus monkeys

HIV affects more than 38 million people worldwide. Although HIV can be effectively treated by lifelong combination antiretroviral therapy, only a handful of patients have been cured. Therapeutic vaccines that induce robust de novo immune responses targeting HIV proteins and latent reservoirs will li...

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Detalles Bibliográficos
Autores principales: Boopathy, Archana V., Sharma, Bhawna, Nekkalapudi, Anurag, Wimmer, Raphaela, Gamez-Guerrero, Maria, Suthram, Silpa, Truong, Hoa, Lee, Johnny, Li, Jiani, Martin, Ross, Blair, Wade, Geleziunas, Romas, Orlinger, Klaus, Ahmadi-Erber, Sarah, Lauterbach, Henning, Makadzange, Tariro, Falkard, Brie, Schmidt, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635999/
https://www.ncbi.nlm.nih.gov/pubmed/37945621
http://dx.doi.org/10.1038/s41541-023-00768-x