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CamoTSS: analysis of alternative transcription start sites for cellular phenotypes and regulatory patterns from 5' scRNA-seq data

Five-prime single-cell RNA-seq (scRNA-seq) has been widely employed to profile cellular transcriptomes, however, its power of analysing transcription start sites (TSS) has not been fully utilised. Here, we present a computational method suite, CamoTSS, to precisely identify TSS and quantify its expr...

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Detalles Bibliográficos
Autores principales: Hou, Ruiyan, Hon, Chung-Chau, Huang, Yuanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636040/
https://www.ncbi.nlm.nih.gov/pubmed/37945584
http://dx.doi.org/10.1038/s41467-023-42636-1