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Genome interpretation in a federated learning context allows the multi-center exome-based risk prediction of Crohn’s disease patients

High-throughput sequencing allowed the discovery of many disease variants, but nowadays it is becoming clear that the abundance of genomics data mostly just moved the bottleneck in Genetics and Precision Medicine from a data availability issue to a data interpretation issue. To solve this empasse it...

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Detalles Bibliográficos
Autores principales: Raimondi, Daniele, Chizari, Haleh, Verplaetse, Nora, Löscher, Britt-Sabina, Franke, Andre, Moreau, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636050/
https://www.ncbi.nlm.nih.gov/pubmed/37945674
http://dx.doi.org/10.1038/s41598-023-46887-2