Gasdermin D promotes hyperinflammation and immunopathology during severe influenza A virus infection

Excessive inflammation and tissue damage during severe influenza A virus (IAV) infection can lead to the development of fatal pulmonary disease. Pyroptosis is a lytic and pro-inflammatory form of cell death executed by the pore-forming protein gasdermin D (GSDMD). In this study, we investigated a po...

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Detalles Bibliográficos
Autores principales: Rosli, Sarah, Harpur, Christopher M., Lam, Maggie, West, Alison C., Hodges, Christopher, Mansell, Ashley, Lawlor, Kate E., Tate, Michelle D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636052/
https://www.ncbi.nlm.nih.gov/pubmed/37945599
http://dx.doi.org/10.1038/s41419-023-06258-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636052/
https://www.ncbi.nlm.nih.gov/pubmed/37945599
http://dx.doi.org/10.1038/s41419-023-06258-1

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