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Gasdermin D promotes hyperinflammation and immunopathology during severe influenza A virus infection
Excessive inflammation and tissue damage during severe influenza A virus (IAV) infection can lead to the development of fatal pulmonary disease. Pyroptosis is a lytic and pro-inflammatory form of cell death executed by the pore-forming protein gasdermin D (GSDMD). In this study, we investigated a po...
Autores principales: | Rosli, Sarah, Harpur, Christopher M., Lam, Maggie, West, Alison C., Hodges, Christopher, Mansell, Ashley, Lawlor, Kate E., Tate, Michelle D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636052/ https://www.ncbi.nlm.nih.gov/pubmed/37945599 http://dx.doi.org/10.1038/s41419-023-06258-1 |
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