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Hypermethylation of the CTRP9 promoter region promotes Hcy induced VSMC lipid deposition and foam cell formation via negatively regulating ER stress

To provide a theoretical basis for the prevention and treatment of atherosclerosis (As), the current study aimed to investigate the mechanism underlying the effect of homocysteine (Hcy) on inducing the lipid deposition and foam cell formation of the vascular smooth muscle cell (VSMC) via C1q/Tumor n...

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Detalles Bibliográficos
Autores principales: Wang, Xiuyu, Ma, Xing, Zeng, Yue, Xu, Lingbo, Zhang, Minghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636064/
https://www.ncbi.nlm.nih.gov/pubmed/37945738
http://dx.doi.org/10.1038/s41598-023-46981-5