Erythropoietin regulates developmental myelination in the brain stimulating postnatal oligodendrocyte maturation

Myelination is a process tightly regulated by a variety of neurotrophic factors. Here, we show—by analyzing two transgenic mouse lines, one overexpressing EPO selectively in the brain Tg21(PDGFB-rhEPO) and another with targeted removal of EPO receptors (EPORs) from oligodendrocyte progenitor cells (...

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Detalles Bibliográficos
Autores principales: Muttathukunnel, Paola, Wälti, Michael, Aboouf, Mostafa A., Köster-Hegmann, Christina, Haenggi, Tatjana, Gassmann, Max, Pannzanelli, Patrizia, Fritschy, Jean-Marc, Schneider Gasser, Edith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636124/
https://www.ncbi.nlm.nih.gov/pubmed/37945644
http://dx.doi.org/10.1038/s41598-023-46783-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636124/
https://www.ncbi.nlm.nih.gov/pubmed/37945644
http://dx.doi.org/10.1038/s41598-023-46783-9

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