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Behavioral, neural and ultrastructural alterations in a graded-dose 6-OHDA mouse model of early-stage Parkinson's disease

Studying animal models furthers our understanding of Parkinson’s disease (PD) pathophysiology by providing tools to investigate detailed molecular, cellular and circuit functions. Different versions of the neurotoxin-based 6-hydroxydopamine (6-OHDA) model of PD have been widely used in rats. However...

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Detalles Bibliográficos
Autores principales: Slézia, Andrea, Hegedüs, Panna, Rusina, Evgeniia, Lengyel, Katalin, Solari, Nicola, Kaszas, Attila, Balázsfi, Diána, Botzanowski, Boris, Acerbo, Emma, Missey, Florian, Williamson, Adam, Hangya, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636184/
https://www.ncbi.nlm.nih.gov/pubmed/37945922
http://dx.doi.org/10.1038/s41598-023-46576-0