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Cryo-EM structure of TMEM63C suggests it functions as a monomer

The TMEM63 family proteins (A, B, and C), calcium-permeable channels in animals that are preferentially activated by hypo-osmolality, have been implicated in various physiological functions. Deficiency of these channels would cause many diseases including hearing loss. However, their structures and...

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Detalles Bibliográficos
Autores principales: Qin, Yuqi, Yu, Daqi, Wu, Dan, Dong, Jiangqing, Li, William Thomas, Ye, Chang, Cheung, Kai Chit, Zhang, Yingyi, Xu, Yun, Wang, YongQiang, Shi, Yun Stone, Dang, Shangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636204/
https://www.ncbi.nlm.nih.gov/pubmed/37945568
http://dx.doi.org/10.1038/s41467-023-42956-2