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Determining epitope specificity of T-cell receptors with transformers

SUMMARY: T-cell receptors (TCRs) on T cells recognize and bind to epitopes presented by the major histocompatibility complex in case of an infection or cancer. However, the high diversity of TCRs, as well as their unique and complex binding mechanisms underlying epitope recognition, make it difficul...

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Detalles Bibliográficos
Autores principales: Khan, Abdul Rehman, Reinders, Marcel J T, Khatri, Indu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636277/
https://www.ncbi.nlm.nih.gov/pubmed/37847663
http://dx.doi.org/10.1093/bioinformatics/btad632