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Ultrafine mapping of chromosome conformation at hundred basepair resolution reveals regulatory genome architecture

The resolution limit of chromatin conformation capture methodologies (3Cs) has restrained their application in detection of fine-level chromatin structure mediated by cis-regulatory elements (CREs). Here, we report two 3C-derived methods, Tri-4C and Tri-HiC, which utilize multirestriction enzyme dig...

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Detalles Bibliográficos
Autores principales: Zhu, Yizhou, Rosenfeld, Michael G., Suh, Yousin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636305/
https://www.ncbi.nlm.nih.gov/pubmed/37922325
http://dx.doi.org/10.1073/pnas.2313285120