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Ultrafine mapping of chromosome conformation at hundred basepair resolution reveals regulatory genome architecture
The resolution limit of chromatin conformation capture methodologies (3Cs) has restrained their application in detection of fine-level chromatin structure mediated by cis-regulatory elements (CREs). Here, we report two 3C-derived methods, Tri-4C and Tri-HiC, which utilize multirestriction enzyme dig...
Autores principales: | Zhu, Yizhou, Rosenfeld, Michael G., Suh, Yousin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636305/ https://www.ncbi.nlm.nih.gov/pubmed/37922325 http://dx.doi.org/10.1073/pnas.2313285120 |
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