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Clinical efficacy and neurobiological correlates of electroconvulsive therapy in patients with clozapine-resistant/intolerant schizophrenia: study protocol of multi-site parallel arm double-blind randomized sham-controlled study

Background: A substantial proportion of patients with treatment resistant schizophrenia do not respond well or partially to clozapine, with a subset that does not tolerate an adequate trial of clozapine. Electroconvulsive therapy (ECT) is regarded as one of the augmenting options, but there is a lac...

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Detalles Bibliográficos
Autores principales: Arumugham, Shyam Sundar, Praharaj, Samir K., Shreekantiah, Umesh, Sreeraj, Vanteemar S., Roy, Chandramouli, Shenoy, Sonia, Purohith, Abhiram Narasimhan, Chithra, Uppinkudru, Bagali, Kiran Basawaraj, Venkataramaiah, Sudhir, Nanjundaiah, Gopala Krishna Kadarapura, Thennarasu, Kandavel, Kumar, Channaveerachari Naveen, Goyal, Nishant, Das, Basudeb, Mehta, Urvakhsh Meherwan, Muralidharan, Kesavan, Venkatasubramanian, Ganesan, Sinha, Preeti, Thirthalli, Jagadisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636350/
https://www.ncbi.nlm.nih.gov/pubmed/37953926
http://dx.doi.org/10.12688/wellcomeopenres.18028.2