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Knockdown of LRRK2 inhibits the progression of lung cancer by regulating TLR4/NF-κB pathways and NLRP3 inflammasome

Leucine-rich repeat kinase 2 (LRRK2) plays an important role in a variety of inflammatory diseases, as well as peripheral and central immune responses. At present, there are few reports about the role of LRRK2 in lung cancer, and need to be further explored. The main purpose of this study is to expl...

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Detalles Bibliográficos
Autores principales: Wu, Junfang, Yang, Shumei, Wu, Hua, Huang, Yongcheng, Miao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636582/
https://www.ncbi.nlm.nih.gov/pubmed/37970545
http://dx.doi.org/10.3164/jcbn.22-122