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Induction of MYCN-amplified neuroblastoma differentiation through NMYC suppression using PPAR-γ antagonist

Neuroblastomas are the most common extracranial solid tumors in children and have a unique feature of neuronal differentiation. Peroxisome proliferator-activated receptor (PPAR)-γ is reported to have neuroprotective effects in addition to having antitumor effects in various cancers. Thus, we aimed t...

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Detalles Bibliográficos
Autores principales: Nakao-Ise, Yukako, Narita, Takumi, Miyamoto, Shingo, Watanabe, Motoki, Tanaka, Takuji, Sowa, Yoshihiro, Iizumi, Yosuke, Masuda, Mitsuharu, Fujii, Gen, Hirai, Yasuko, Nakao, Toshimasa, Takakura, Hideki, Mutoh, Michihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636585/
https://www.ncbi.nlm.nih.gov/pubmed/37970556
http://dx.doi.org/10.3164/jcbn.23-28