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Botulinum neurotoxin A modulates the axonal release of pathological tau in hippocampal neurons

Pathological tau aggregates propagate across functionally connected neuronal networks in human neurodegenerative pathologies, such as Alzheimer's disease. However, the mechanism underlying this process is poorly understood. Several studies have showed that tau release is dependent on neuronal a...

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Detalles Bibliográficos
Autores principales: Panzi, Chiara, Surana, Sunaina, De La-Rocque, Samantha, Moretto, Edoardo, Lazo, Oscar Marcelo, Schiavo, Giampietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636589/
https://www.ncbi.nlm.nih.gov/pubmed/37037273
http://dx.doi.org/10.1016/j.toxicon.2023.107110