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P53‑microRNA interactions regulate the response of colorectal tumor cells to oxaliplatin under normoxic and hypoxic conditions

Oxaliplatin (OXA)-containing regimens are used as first-line chemotherapy in colorectal cancer (CRC). However, OXA resistance remains a major challenge in CRC treatment. CRC cells that adapt to hypoxia can potentially develop OXA resistance, and the underlying molecular mechanisms still need to be f...

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Detalles Bibliográficos
Autores principales: Zhang, Jiayu, Li, Chenguang, Sun, Luanbiao, Sun, Denghua, Zhao, Tiancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636723/
https://www.ncbi.nlm.nih.gov/pubmed/37921068
http://dx.doi.org/10.3892/or.2023.8656