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Phosphorylated HP1α–Nucleosome Interactions in Phase Separated Environments

[Image: see text] In the nucleus, transcriptionally silent genes are sequestered into heterochromatin compartments comprising nucleosomes decorated with histone H3 Lys9 trimethylation and a protein called HP1α. This protein can form liquid–liquid droplets in vitro and potentially organize heterochro...

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Detalles Bibliográficos
Autores principales: Elathram, Nesreen, Ackermann, Bryce E., Clark, Evan T., Dunn, Shelby R., Debelouchina, Galia T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636758/
https://www.ncbi.nlm.nih.gov/pubmed/37870432
http://dx.doi.org/10.1021/jacs.3c06481