Cargando…
Phosphorylated HP1α–Nucleosome Interactions in Phase Separated Environments
[Image: see text] In the nucleus, transcriptionally silent genes are sequestered into heterochromatin compartments comprising nucleosomes decorated with histone H3 Lys9 trimethylation and a protein called HP1α. This protein can form liquid–liquid droplets in vitro and potentially organize heterochro...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636758/ https://www.ncbi.nlm.nih.gov/pubmed/37870432 http://dx.doi.org/10.1021/jacs.3c06481 |