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Conformationally Restricted Glycopeptide Backbone Inhibits Gas-Phase H/D Scrambling between Glycan and Peptide Moieties

[Image: see text] Protein glycosylation is a common post-translational modification on extracellular proteins. The conformational dynamics of several glycoproteins have been characterized by hydrogen/deuterium exchange mass spectrometry (HDX-MS). However, it is, in most cases, not possible to extrac...

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Detalles Bibliográficos
Autores principales: Code, Christian, Qiu, Danwen, Solov’yov, Ilia A., Lee, Jung-Goo, Shin, Hyeon-Cheol, Roland, Christopher, Sagui, Celeste, Houde, Damian, Rand, Kasper D., Jørgensen, Thomas J. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636759/
https://www.ncbi.nlm.nih.gov/pubmed/37883679
http://dx.doi.org/10.1021/jacs.3c04068