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Loss of Krüppel-like factor-10 facilitates the development of chemical-induced liver cancer in mice

BACKGROUND: Krüppel-like factor 10 (KLF10) is involved in a positive feedback loop that regulates transforming growth factor β (TGFβ) signaling, and TGFβ plays an important role in the pathogenesis of liver disease. Here, we investigated whether KLF10 deletion affects the development of liver fibros...

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Detalles Bibliográficos
Autores principales: Yoo, Sung Hwan, Nahm, Ji Hae, Lee, Woon Kyu, Lee, Hyun Woong, Chang, Hye Young, Lee, Jung Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636809/
https://www.ncbi.nlm.nih.gov/pubmed/37946098
http://dx.doi.org/10.1186/s10020-023-00751-1