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System analysis based on the pyroptosis-related genes identifes GSDMD as a novel therapy target for skin cutaneous melanoma

BACKGROUND: Skin cutaneous melanoma (SKCM) is the most aggressive skin cancer, accounting for more than 75% mortality rate of skin-related cancers. As a newly identified programmed cell death, pyroptosis has been found to be closely associated with tumor progression. Nevertheless, the prognostic sig...

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Detalles Bibliográficos
Autores principales: Zhao, Shixin, Zhu, Yongkang, Liu, Hengdeng, He, Xuefeng, Xie, Julin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636830/
https://www.ncbi.nlm.nih.gov/pubmed/37950289
http://dx.doi.org/10.1186/s12967-023-04513-9