Pharmacological inhibition of the cysteine protease cathepsin C improves graft function after heart transplantation in rats

BACKGROUND: Heart transplantation (HTX) is the standard treatment for end-stage heart failure. However, reperfusion following an ischemic period can contribute to myocardial injury. Neutrophil infiltration, along with the subsequent release of tissue-degrading neutrophil elastase (NE)-related serine...

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Detalles Bibliográficos
Autores principales: Liu, Baoer, Korkmaz, Brice, Kraft, Patricia, Mayer, Tobias, Sayour, Alex A., Grundl, Marc A., Domain, Roxane, Karck, Matthias, Szabó, Gábor, Korkmaz-Icöz, Sevil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636924/
https://www.ncbi.nlm.nih.gov/pubmed/37946197
http://dx.doi.org/10.1186/s12967-023-04659-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636924/
https://www.ncbi.nlm.nih.gov/pubmed/37946197
http://dx.doi.org/10.1186/s12967-023-04659-6

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