Glutamine deficiency drives transforming growth factor‐β signaling activation that gives rise to myofibroblastic carcinoma‐associated fibroblasts

Tumor‐promoting carcinoma‐associated fibroblasts (CAFs), abundant in the mammary tumor microenvironment (TME), maintain transforming growth factor‐β (TGF‐β)‐Smad2/3 signaling activation and the myofibroblastic state, the hallmark of activated fibroblasts. How myofibroblastic CAFs (myCAFs) arise in t...

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Detalles Bibliográficos
Autores principales: Mezawa, Yoshihiro, Wang, Tingwei, Daigo, Yataro, Takano, Atsushi, Miyagi, Yohei, Yokose, Tomoyuki, Yamashita, Toshinari, Yang, Liying, Maruyama, Reo, Seimiya, Hiroyuki, Orimo, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637058/
https://www.ncbi.nlm.nih.gov/pubmed/37706357
http://dx.doi.org/10.1111/cas.15955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637058/
https://www.ncbi.nlm.nih.gov/pubmed/37706357
http://dx.doi.org/10.1111/cas.15955

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