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Branched‐chain keto‐acid dehydrogenase kinase regulates vascular permeability and angiogenesis to facilitate tumor metastasis in renal cell carcinoma

Branched‐chain keto‐acid dehydrogenase kinase (BCKDK) is the rate‐limiting enzyme of branched‐chain amino acid (BCAA) metabolism. In the last six years, BCKDK has been used as a kinase to promote tumor proliferation and metastasis. Renal cell carcinoma (RCC) is a highly vascularized tumor. A high de...

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Detalles Bibliográficos
Autores principales: Yang, Kunao, Xu, Chunlan, Sun, Huimin, Xuan, Zuodong, Liu, Yankuo, Li, Jinxin, Bai, Yang, Zheng, Zeyuan, Zhao, Yue, Shi, Zhiyuan, Zheng, Jianzhong, Shao, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637060/
https://www.ncbi.nlm.nih.gov/pubmed/37715534
http://dx.doi.org/10.1111/cas.15956