β-sitosterol alleviates dextran sulfate sodium-induced experimental colitis via inhibition of NLRP3/Caspase-1/GSDMD-mediated pyroptosis

Background: Inflammation-related NLRP3/Caspase-1/GSDMD-mediated pyroptosis is involved in the progression of ulcerative colitis (UC). β-sitosterol (SIT) was reported to have anti-inflammatory effects on experimental colitis, while the regulation of SIT on pyroptosis is unclear. Therefore, the presen...

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Detalles Bibliográficos
Autores principales: Zhang, Di, Ge, Fei, Ji, Jing, Li, Yu-Jing, Zhang, Fu-Rong, Wang, Shu-Yan, Zhang, Shu-Jing, Zhang, Dong-Mei, Chen, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637366/
https://www.ncbi.nlm.nih.gov/pubmed/37954856
http://dx.doi.org/10.3389/fphar.2023.1218477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637366/
https://www.ncbi.nlm.nih.gov/pubmed/37954856
http://dx.doi.org/10.3389/fphar.2023.1218477

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