Bone marrow stromal cells reduce low-dose cytarabine-induced differentiation of acute myeloid leukemia

Low-dose cytarabine (LDAC) is a standard therapy for elderly acute myeloid leukemia (AML) patients unfit for intensive chemotherapy. While high doses of cytarabine induce cytotoxicity, the precise mechanism of action of LDAC in AML remains elusive. In vitro studies have demonstrated LDAC-induced dif...

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Detalles Bibliográficos
Autores principales: Smoljo, Tomislav, Tomic, Barbara, Lalic, Hrvoje, Dembitz, Vilma, Batinic, Josip, Bedalov, Antonio, Visnjic, Dora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637411/
https://www.ncbi.nlm.nih.gov/pubmed/37954840
http://dx.doi.org/10.3389/fphar.2023.1258151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637411/
https://www.ncbi.nlm.nih.gov/pubmed/37954840
http://dx.doi.org/10.3389/fphar.2023.1258151

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