TWIST1 and TSG6 are coordinately regulated and function as potency biomarkers in human MSCs

Mesenchymal stem/stromal cells (MSCs) have been evaluated in >1500 clinical trials, but outcomes remain suboptimal because of knowledge gaps in quality attributes that confer potency. We show that TWIST1 directly represses TSG6 expression that TWIST1 and TSG6 are inversely correlated across bone...

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Detalles Bibliográficos
Autores principales: Lee, Ryang Hwa, Boregowda, Siddaraju V., Shigemoto-Kuroda, Taeko, Bae, EunHye, Haga, Christopher L., Abbery, Colette A., Bayless, Kayla J., Haskell, Andrew, Gregory, Carl A., Ortiz, Luis A., Phinney, Donald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637745/
https://www.ncbi.nlm.nih.gov/pubmed/37948519
http://dx.doi.org/10.1126/sciadv.adi2387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637745/
https://www.ncbi.nlm.nih.gov/pubmed/37948519
http://dx.doi.org/10.1126/sciadv.adi2387

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