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Evolutionary adaptation to juvenile malnutrition impacts adult metabolism and impairs adult fitness in Drosophila

Juvenile undernutrition has lasting effects on adult metabolism of the affected individuals, but it is unclear how adult physiology is shaped over evolutionary time by natural selection driven by juvenile undernutrition. We combined RNAseq, targeted metabolomics, and genomics to study the consequenc...

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Detalles Bibliográficos
Autores principales: Erkosar, Berra, Dupuis, Cindy, Cavigliasso, Fanny, Savary, Loriane, Kremmer, Laurent, Gallart-Ayala, Hector, Ivanisevic, Julijana, Kawecki, Tadeusz J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637773/
https://www.ncbi.nlm.nih.gov/pubmed/37847744
http://dx.doi.org/10.7554/eLife.92465