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Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature

The ovarian microenvironment becomes fibrotic and stiff with age, in part due to increased collagen and decreased hyaluronan. However, the extracellular matrix (ECM) is a complex network of hundreds of proteins, glycoproteins, and glycans which are highly tissue specific and undergo pronounced chang...

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Detalles Bibliográficos
Autores principales: Dipali, Shweta S., King, Christina D., Rose, Jacob P., Burdette, Joanna E., Campisi, Judith, Schilling, Birgit, Duncan, Francesca E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637783/
https://www.ncbi.nlm.nih.gov/pubmed/37899138
http://dx.doi.org/10.18632/aging.205190