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Icariin improves cognitive impairment by inhibiting ferroptosis of nerve cells

Aim: We investigated the effect and mechanism of Icariin (ICA) on improving neurobehavioral ability of mice with Alzheimer's disease (AD). Methods: We selected 10-month-old APP/PS1 mice (AD) and wild-type C57BL/6J mice (Normal). After intragastric administration of ICA, Morris water maze was em...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Fu, Yiming, Qin, Zhipeng, Pei, Hongyan, Zhai, Liping, Guan, Qiaobing, Wu, Shasha, Shen, Heping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637794/
https://www.ncbi.nlm.nih.gov/pubmed/37889523
http://dx.doi.org/10.18632/aging.205144