Copine7 deficiency leads to hepatic fat accumulation via mitochondrial dysfunction

OBJECTIVE: Mitochondrial dysfunction affects hepatic lipid homeostasis and promotes ROS generation. Copine7 (CPNE7) belongs to the ubiquitous copine family of calcium-dependent phospholipid binding proteins. CPNE7 has a high calcium ion binding affinity and the capacity to scavenge reactive oxygen s...

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Detalles Bibliográficos
Autores principales: Hwang, Geumbit, Seo, Hyejin, Park, Joo-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637907/
https://www.ncbi.nlm.nih.gov/pubmed/37954344
http://dx.doi.org/10.1016/j.heliyon.2023.e21676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637907/
https://www.ncbi.nlm.nih.gov/pubmed/37954344
http://dx.doi.org/10.1016/j.heliyon.2023.e21676

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